KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF5C
All Species:
14.85
Human Site:
S534
Identified Species:
23.33
UniProt:
O60282
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60282
NP_004513.1
957
109495
S534
T
T
T
Q
R
E
L
S
Q
L
Q
E
L
S
N
Chimpanzee
Pan troglodytes
XP_525938
860
98662
V482
T
L
A
D
V
N
G
V
I
E
E
E
F
T
M
Rhesus Macaque
Macaca mulatta
XP_001082054
860
98340
V482
T
L
A
D
V
N
G
V
I
E
E
E
F
T
M
Dog
Lupus familis
XP_533351
955
109129
S533
T
T
T
Q
R
E
L
S
Q
L
Q
E
L
S
N
Cat
Felis silvestris
Mouse
Mus musculus
P28738
956
109222
S533
T
T
T
Q
R
E
L
S
Q
L
Q
E
L
S
N
Rat
Rattus norvegicus
Q6QLM7
1027
116897
Q534
L
S
L
E
S
E
P
Q
R
L
Q
E
V
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508129
965
109909
Q538
A
S
I
D
A
E
L
Q
K
L
K
E
M
T
N
Chicken
Gallus gallus
Q90640
1225
138905
S640
E
S
T
E
R
T
V
S
K
L
N
Q
E
I
R
Frog
Xenopus laevis
Q91784
1226
138905
A637
E
S
T
E
K
T
V
A
K
M
N
Q
E
I
Q
Zebra Danio
Brachydanio rerio
NP_001116747
985
113653
S530
A
G
V
E
R
D
L
S
S
L
K
E
L
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17210
975
110381
Q554
N
A
A
S
T
E
L
Q
Q
L
K
D
M
S
S
Honey Bee
Apis mellifera
XP_395236
988
112484
Q555
N
S
T
A
S
E
L
Q
Q
L
R
D
M
S
A
Nematode Worm
Caenorhab. elegans
P34540
815
91875
L459
V
S
Q
E
L
E
K
L
R
Q
Q
V
L
L
Q
Sea Urchin
Strong. purpuratus
P35978
1031
117504
Q525
H
T
T
S
T
E
L
Q
K
L
Q
E
L
E
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
K543
L
D
M
K
M
S
A
K
E
T
S
A
V
L
D
Conservation
Percent
Protein Identity:
100
89.8
85.5
98.3
N.A.
98
69.8
N.A.
75.2
26.3
24.8
76.8
N.A.
62
63.2
45.3
61.4
Protein Similarity:
100
89.8
86.4
98.9
N.A.
99.1
81.6
N.A.
86.4
45.3
45.5
86.9
N.A.
77.6
77.9
61.3
74.7
P-Site Identity:
100
13.3
13.3
100
N.A.
100
33.3
N.A.
33.3
26.6
6.6
46.6
N.A.
33.3
40
20
53.3
P-Site Similarity:
100
26.6
26.6
100
N.A.
100
60
N.A.
66.6
60
60
66.6
N.A.
60
66.6
40
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
31.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
52.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
7
20
7
7
0
7
7
0
0
0
7
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
20
0
7
0
0
0
0
0
14
0
0
7
% D
% Glu:
14
0
0
34
0
60
0
0
7
14
14
60
14
7
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
14
0
0
% F
% Gly:
0
7
0
0
0
0
14
0
0
0
0
0
0
0
7
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
0
0
0
0
14
0
0
0
0
14
0
% I
% Lys:
0
0
0
7
7
0
7
7
27
0
20
0
0
0
0
% K
% Leu:
14
14
7
0
7
0
54
7
0
67
0
0
40
14
0
% L
% Met:
0
0
7
0
7
0
0
0
0
7
0
0
20
0
14
% M
% Asn:
14
0
0
0
0
14
0
0
0
0
14
0
0
0
27
% N
% Pro:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
20
0
0
0
34
34
7
40
14
0
0
20
% Q
% Arg:
0
0
0
0
34
0
0
0
14
0
7
0
0
0
7
% R
% Ser:
0
40
0
14
14
7
0
34
7
0
7
0
0
47
7
% S
% Thr:
34
27
47
0
14
14
0
0
0
7
0
0
0
20
0
% T
% Val:
7
0
7
0
14
0
14
14
0
0
0
7
14
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _